Opportunity Information: Apply for RFA HL 20 004
This funding opportunity (RFA-HL-20-004) is a National Institutes of Health, National Heart, Lung, and Blood Institute (NHLBI) cooperative agreement (U24) to create a single Research Coordinating Center (RCC) for the DECIPHeR program, which stands for Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk. The broader DECIPHeR initiative (supported under a companion award, RFA-HL-20-003) focuses on late-stage, or T4, implementation research. In this context, T4 implementation research means studying practical strategies that help proven, evidence-based interventions actually get adopted, maintained, and embedded in routine real-world settings like clinics, public health systems, and community organizations. The goal is not to invent brand-new clinical treatments, but to improve how well effective interventions are delivered at scale, over time, in communities experiencing a high burden of cardiovascular and/or pulmonary disease and related inequities.
The RCC is essentially the operational backbone of the DECIPHeR network. Rather than running its own clinical trial, the coordinating center supports and aligns multiple independently funded DECIPHeR projects so they function as a coherent program. A central emphasis is reducing or eliminating heart and lung health disparities by strengthening the delivery and sustainability of multi-level interventions, meaning interventions that may act at more than one layer at once (for example, individual behavior support combined with health system workflow changes and community-level access improvements). The RCC is expected to help the network generate greater collective impact than each project could achieve alone by standardizing core processes, facilitating cross-project learning, and ensuring consistent oversight and communication.
A major part of the RCC role is coordination and convening. The center is responsible for organizing and managing network governance activities such as steering committee meetings and working groups, using both in-person and virtual formats. This includes the practical logistics (scheduling, agendas, minutes, documentation) as well as the collaborative infrastructure that keeps teams connected and productive. Beyond internal coordination, the RCC also promotes communication among investigators and with the broader research and practice community, helping results and lessons learned travel beyond the funded sites and inform future implementation efforts.
Another prominent responsibility is network outreach and skills development in implementation science. The RCC is expected to plan and coordinate activities that build capacity across the network, such as shared training, webinars, workshops, toolkits, or other professional development opportunities. The intent is to strengthen the ability of DECIPHeR investigators and partners to use rigorous implementation science methods, measure implementation outcomes, and apply best practices for scaling and sustaining evidence-based interventions in real-world settings. This workforce and infrastructure development component is central to making the program durable and influential beyond the award period.
The opportunity also places strong emphasis on oversight and monitoring. The RCC must organize, implement, and manage a global implementation Data Safety and Monitoring Board (DSMB) for the DECIPHeR awards. Even though the FOA is labeled "Clinical Trial Not Allowed" for the coordinating center, the supported DECIPHeR projects involve implementation research in real communities and systems, which still requires careful monitoring of participant safety, ethical conduct, and study integrity. The RCC is additionally tasked with providing clinical study and site monitoring for DECIPHeR awards, which typically includes developing monitoring plans, coordinating reporting, tracking protocol adherence where applicable, ensuring consistent documentation practices, and helping address issues identified during monitoring in a timely and standardized way across projects.
From an administrative standpoint, the award is offered as a cooperative agreement, which generally means NIH/NHLBI anticipates having substantial involvement with the awardee compared with a standard grant. Applicants should expect an active partnership with NHLBI staff, clear deliverables, and ongoing coordination requirements across the network. Only one award is expected, underscoring that this is a single centralized hub rather than multiple coordinating centers.
Key details from the posting include an award ceiling of $485,000 and an expected number of awards of 1. The opportunity falls under the Health activity category and lists CFDA numbers 93.837, 93.838, and 93.840. Eligible applicants are broad and include various government entities (state, county, city/township, special districts), independent school districts, public and private institutions of higher education, federally recognized Native American tribal governments and other tribal organizations, public housing/Indian housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and other eligible entities as specified in the full announcement. The opportunity was created March 11, 2019, with an original closing date of October 1, 2019.
In practical terms, a strong RCC application for this FOA would be expected to show deep capability in multi-site coordination, facilitation of cross-project collaboration, implementation science training and dissemination, and robust governance for monitoring and DSMB operations. The center would need to demonstrate it can keep a complex network aligned, support consistent high-quality implementation research practices, and help DECIPHeR projects collectively accelerate sustainable adoption of interventions that measurably reduce heart and lung health disparities in high-burden communities.Apply for RFA HL 20 004
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) - Research Coordinating Center (RCC) (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837, 93.838, 93.840.
- This funding opportunity was created on Mar 11, 2019.
- Applicants must submit their applications by Oct 01, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $485,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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