Opportunity Information: Apply for RFA HD 16 040
The National Institutes of Health (NIH) announced this funding opportunity (RFA HD 16 040) to support a single Coordinating Center (CC) for the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The award mechanism is a U24 cooperative agreement, meaning NIH expects to be substantially involved in the work alongside the awardee rather than simply providing funds with minimal interaction. The Coordinating Center is intended to serve as the operational backbone for the ATN Cooperative Research Program awards funded under a companion initiative (RFA-HD-16-035), making sure the network can run complex, multi-site research in a consistent, high-quality, and efficient way.
At its core, the grant is about building and maintaining the data management, coordination, and logistical support infrastructure needed to plan and conduct research trials focused on adolescents and young adults affected by HIV. The ATN is expected to have the capacity to develop and run a broad range of studies, including behavioral interventions, community-based approaches, translational research, therapeutic trials, and prevention technologies such as microbicides and vaccines. The target population is youth ages 12 to 24, and the announcement explicitly highlights the importance of including minors, which signals that applicants should be prepared to handle the ethical, regulatory, and practical complexities of enrolling and protecting participants under 18.
Because this is a Coordinating Center opportunity, the emphasis is less on proposing a single standalone clinical study and more on demonstrating the ability to support an entire network of studies and sites. In practical terms, that typically includes centralized data systems, uniform procedures for collecting and managing study data, coordination across multiple investigators and locations, and operational support that keeps protocols, timelines, reporting, and communications aligned. The NIH also encourages applicants with innovative thinking and novel approaches to addressing adolescent public health challenges, reflecting an interest in teams that can not only manage logistics but also help the network function creatively and responsively as new scientific questions and prevention/treatment tools emerge.
Eligibility is broad across public and private sectors. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments; tribal organizations (including those other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations other than small businesses; small businesses; and other eligible entities. The announcement also calls out categories of organizations that are particularly encouraged or explicitly recognized as eligible, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
At the same time, the FOA is clear that foreign participation is not allowed in this particular award. Non-domestic (non-U.S.) entities cannot apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not permitted. This means the Coordinating Center and its supported operations must be fully domestic in scope and implementation.
Administrative details in the source information indicate the opportunity falls under the “Discretionary” category and is associated with several CFDA numbers (93.242, 93.279, 93.307, 93.865), reflecting NIH program linkages. NIH anticipated making one award under this announcement. The original closing date listed was January 19, 2016, and the opportunity was created on September 24, 2015. The listing does not specify an award ceiling amount in the provided text, but it does clearly communicate that the expectation is for one Coordinating Center to provide the central infrastructure that enables the ATN to carry out its research mission with a strong focus on adolescents and young adults, including minors, who are at risk for HIV or living with HIV.Apply for RFA HD 16 040
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Adolescent Medicine Trials Network for HIV/AIDS Interventions(ATN) Coordinating Center (CC) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242, 93.279, 93.307, 93.865.
- This funding opportunity was created on 2015-09-24.
- Applicants must submit their applications by 2016-01-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQ)
1. What is this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity announcement (FOA) identified as RFA HD 16 040. It funds a single Coordinating Center (CC) for the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN).
2. What is the purpose of the Coordinating Center (CC)?
The Coordinating Center is intended to serve as the operational backbone for the ATN Cooperative Research Program. Its role is to build and maintain the infrastructure needed to plan and conduct complex, multi-site research in a consistent, high-quality, and efficient way.
3. How many awards does NIH anticipate making under this announcement?
NIH anticipated making one award under this announcement.
4. What award mechanism is being used?
The award mechanism is a U24 cooperative agreement. This means NIH expects to be substantially involved in the work alongside the awardee rather than simply providing funds with minimal interaction.
5. How is a U24 cooperative agreement different from a typical grant?
Based on the FOA description, NIH will have substantial involvement in the project. In practice, this implies more active collaboration and coordination with NIH compared with grant mechanisms where the funder has more limited engagement after award.
6. Is this opportunity about running one clinical trial?
No. The emphasis is less on proposing a single standalone clinical study and more on demonstrating the ability to support an entire network of studies and sites. The CC is expected to provide centralized coordination, data management, and logistical support across multiple research efforts.
7. What kinds of research is the ATN expected to support?
The ATN is expected to have the capacity to develop and run a broad range of studies, including behavioral interventions, community-based approaches, translational research, therapeutic trials, and prevention technologies such as microbicides and vaccines.
8. What population is the network focused on?
The target population is adolescents and young adults ages 12 to 24, including youth at risk for HIV and youth living with HIV.
9. Does the FOA specifically emphasize including minors?
Yes. The announcement explicitly highlights the importance of including minors, signaling that applicants should be prepared for the ethical, regulatory, and practical complexities of enrolling and protecting participants under age 18.
10. What does the Coordinating Center need to be able to do operationally?
The FOA indicates the CC should provide the infrastructure needed for network operations, typically including centralized data systems, uniform procedures for collecting and managing study data, coordination across investigators and locations, and operational support to keep protocols, timelines, reporting, and communications aligned.
11. How does this FOA relate to other NIH initiatives mentioned?
The Coordinating Center is intended to support the ATN Cooperative Research Program awards funded under a companion initiative identified as RFA-HD-16-035.
12. Is NIH encouraging any particular approach or mindset from applicants?
Yes. NIH encourages applicants with innovative thinking and novel approaches to addressing adolescent public health challenges, indicating interest in teams that can support network operations while also helping the network function creatively and responsively as new scientific questions and tools emerge.
13. Who is eligible to apply?
Eligibility is broad across public and private sectors. Eligible applicants include various levels of government (state, county, city/township, special district), independent school districts, public and private institutions of higher education, federally recognized tribal governments, tribal organizations, public housing authorities/Indian housing authorities, nonprofits (with or without 501(c)(3) status), for-profit organizations other than small businesses, small businesses, and other eligible entities.
14. Are any specific organization types called out as encouraged or explicitly recognized?
Yes. The FOA explicitly recognizes or encourages participation from organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
15. Are foreign (non-U.S.) organizations allowed to apply?
No. Foreign participation is not allowed. Non-domestic (non-U.S.) entities cannot apply.
16. Can a U.S. organization apply if it has a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible under this FOA, and foreign components (as defined by NIH policy) are not permitted.
17. Does the FOA allow the Coordinating Center to operate internationally?
No. The FOA states that foreign components are not permitted, meaning the Coordinating Center and its supported operations must be fully domestic in scope and implementation.
18. What is the opportunity category?
The opportunity is listed under the "Discretionary" category.
19. Which CFDA numbers are associated with this opportunity?
The FOA listing is associated with CFDA numbers 93.242, 93.279, 93.307, and 93.865.
20. When was the opportunity created and what was the original closing date?
The opportunity was created on September 24, 2015. The original closing date listed was January 19, 2016.
21. Is an award ceiling amount provided in the information available here?
No. The provided text does not specify an award ceiling amount.
22. What is the main takeaway for prospective applicants?
The central expectation is to propose and demonstrate the capacity to run the core coordination, data management, and logistical infrastructure for the ATN, enabling high-quality, efficient multi-site research focused on HIV-related interventions for youth ages 12 to 24, including minors, within a fully domestic (U.S.-only) operational scope.
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