Opportunity Information: Apply for PA 18 672
The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33), funding opportunity number PA-18-672, is an NIH discretionary grant mechanism meant to support senior or experienced scientists who are at a point in their careers where additional, structured research training would meaningfully change what they can do as investigators. The fellowship is specifically framed for people who want to pivot in a major way (for example, moving into a new discipline, adopting a substantially different research approach, or entering a new scientific area) or who want to broaden and modernize their scientific skill set by gaining new research capabilities. In practical terms, it is designed to fund a mentored training period that helps an established researcher retool, expand into a new research direction, and come out of the fellowship better positioned to conduct independent research aligned with the missions of participating NIH Institutes and Centers.
A central feature of this particular Parent F33 announcement is its boundary around clinical trials. It is intended for applicants whose proposed fellowship research and training plan does not include leading an independent clinical trial, conducting a clinical trial feasibility study as the leader, or running an ancillary study to a clinical trial as the leader. At the same time, it does not shut the door on clinical trial exposure altogether: applicants are allowed to propose a research experience that is connected to a clinical trial as long as the trial itself is led by a sponsor or co-sponsor (in other words, the fellow is not the person responsible for leading the trial). This makes the FOA a fit for senior investigators who may want clinical research experience, exposure to trial infrastructure, or training in trial-related methods, but whose fellowship aims are not centered on being the primary driver of a trial.
Eligibility spans a broad range of organization types, reflecting NIH-wide participation and the goal of supporting training across many sectors. Eligible applicants listed in the source include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) nonprofits that are not institutions of higher education), for-profit organizations other than small businesses, and small businesses. The FOA also highlights additional eligible applicant categories that NIH often calls out to encourage participation from a wide set of institutions and communities, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal government agencies, and non-domestic (non-U.S.) entities (foreign organizations). The announcement notes that applicants should consult the FOA for the full eligibility details and any specific conditions that may apply to particular organization types.
From an administrative standpoint, the opportunity is offered by the National Institutes of Health under the broader NRSA training authority and is categorized under education, environment, and health-related funding activity areas. The CFDA numbers associated with the listing are 93.113, 93.121, 93.273, 93.279, 93.361, 93.398, 93.846, 93.859, and 93.866, which reflect the multiple NIH Institutes and Centers that may participate and support awards under their respective program areas. The record provided shows an original closing date of 2019-02-21 and a creation date of 2018-02-20; it does not list an award ceiling or expected number of awards in the supplied fields, so those specifics would need to be confirmed directly in the full FOA or related NIH documentation.
Overall, this Parent F33 NRSA senior fellowship is best understood as a mentored re-training or career-expansion award for established scientists: it supports a deliberate, structured plan to acquire new expertise and research capability in areas relevant to NIH priorities, while clearly steering applicants away from proposing to lead independent clinical trials under this particular announcement.Apply for PA 18 672
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.273, 93.279, 93.361, 93.398, 93.846, 93.859, 93.866.
- This funding opportunity was created on 2018-02-20.
- Applicants must submit their applications by 2019-02-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the Ruth L. Kirschstein NRSA Individual Senior Fellowship (Parent F33)?
The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) is an NIH discretionary grant mechanism that supports a mentored, structured period of research training for senior or experienced scientists. It is designed for established investigators who want additional training that would meaningfully expand or change their capabilities as independent researchers.
What is the funding opportunity number for this fellowship?
The funding opportunity number is PA-18-672.
What is the main purpose of this F33 opportunity?
The primary purpose is to fund a mentored training experience that helps an established researcher retool or expand into a new research direction. The training is intended to leave the fellow better positioned to conduct independent research aligned with the missions of participating NIH Institutes and Centers.
Who is this fellowship meant for?
This fellowship is aimed at senior or experienced scientists who are at a point in their careers where additional, structured research training would significantly change what they can do as investigators. It is particularly oriented toward people seeking substantial growth or redirection rather than incremental skill-building.
What kinds of career changes or training goals does the Parent F33 emphasize?
The announcement emphasizes major pivots or meaningful modernization of an investigator's skill set. Examples described include moving into a new discipline, adopting a substantially different research approach, entering a new scientific area, or broadening and updating research capabilities in a way that supports a new or expanded independent research trajectory.
Is this a mentored award or an independent research grant?
Based on the description provided, this is a mentored training fellowship intended to support a structured training period. The focus is on gaining new expertise and capabilities through a defined training plan, rather than simply funding an independent research project without a training component.
How does this Parent F33 FOA handle clinical trials?
A central boundary in this Parent F33 announcement is that the proposed fellowship research and training plan should not include leading an independent clinical trial, leading a clinical trial feasibility study, or leading an ancillary study to a clinical trial. In other words, the fellowship is not intended to support the fellow as the person responsible for running a trial.
Are any clinical trial-related activities allowed under this fellowship?
Yes. Clinical trial exposure is not fully excluded. The fellow may propose a research experience that is connected to a clinical trial as long as the clinical trial itself is led by a sponsor or co-sponsor (meaning the fellow is not the leader responsible for the trial). This can make the FOA suitable for senior investigators seeking experience with clinical research settings or trial-related methods without serving as the trial leader.
What does it mean that the clinical trial must be led by a sponsor or co-sponsor?
It means the clinical trial leadership responsibility sits with an external sponsor or co-sponsor rather than with the fellow. The fellowship research experience can be associated with that trial, but the fellow should not be positioned as the person leading the trial, leading a feasibility study, or leading an ancillary trial study.
What types of organizations are eligible to apply?
Eligible applicants include a wide range of organization types, such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3) nonprofits that are not institutions of higher education), for-profit organizations other than small businesses, and small businesses.
Are specialized institution categories included as eligible applicants?
Yes. The FOA highlights additional eligible applicant categories often emphasized by NIH, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal government agencies, and non-domestic (non-U.S.) entities (foreign organizations).
Can foreign organizations apply?
Yes. The eligibility information provided includes non-domestic (non-U.S.) entities (foreign organizations) among the eligible applicant categories, with the note that applicants should consult the FOA for full eligibility details and any specific conditions that may apply.
Is a federal government agency eligible to apply?
Yes. The opportunity lists eligible federal government agencies among the eligible applicant categories.
What federal agency offers this opportunity?
The opportunity is offered by the National Institutes of Health (NIH) under the broader NRSA training authority.
What are the funding activity areas for this opportunity?
The opportunity is categorized under education, environment, and health-related funding activity areas.
Which NIH programs or Institutes and Centers support awards under this listing?
The description indicates participation by multiple NIH Institutes and Centers, reflected by the set of associated CFDA numbers. Awards may align with the missions of participating NIH Institutes and Centers, and applicants are expected to propose training and research aligned with those missions.
What CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.113, 93.121, 93.273, 93.279, 93.361, 93.398, 93.846, 93.859, and 93.866.
Does the provided listing include an award ceiling or the expected number of awards?
No. The supplied fields do not list an award ceiling or an expected number of awards. Those details would need to be confirmed in the full FOA or related NIH documentation.
What dates are included in the record provided?
The record shows a creation date of 2018-02-20 and an original closing date of 2019-02-21.
Is this fellowship best suited for incremental training or for major career expansion?
The description frames it as best understood as a mentored re-training or career-expansion award for established scientists, with an emphasis on significant pivots or meaningful modernization of skills rather than small, incremental adjustments.
What should applicants do to confirm any conditions or full eligibility details?
The description notes that applicants should consult the FOA for the full eligibility details and any specific conditions that may apply to particular organization types or applicant situations.
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